EFFECTIVE RESPONSE TO HUMAN TRAFFICKING IN SOUTH AFRICA: LAW AS A TOOTHLESS BULLDOG


Deubiquitination of epidermal growth factor receptor by ubiquitin-specific peptidase 54 enhances drug sensitivity to gefitinib in gefitinib-resistant non-small cell lung cancer cells.

A precise balance between ubiquitination and deubiquitination is crucial for cellular regulation.Ubiquitin-specific peptidase 54 (USP54), an active deubiquitinase (DUB), modulates the ubiquitination of the epidermal growth factor receptor (EGFR).While the significance of USP54 in tumorigenesis is known, its specific function in cancer progression r

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Optimizing reproducibility of operant testing through reinforcer standardization: identification of key nutritional constituents determining reward strength in touchscreens

Abstract Reliable and reproducible assessment of animal learning and behavior is a central aim of basic and translational neuroscience research.Recent developments in automated operant chamber technology have led to the possibility of universal standard protocols, in addition to increased translational potential, reliability and accuracy.However, t

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MSPM: A modularized and scalable multi-agent reinforcement learning-based system for financial portfolio management

Financial portfolio management (PM) is one of the most applicable problems in reinforcement learning (RL) owing to its sequential decision-making nature.However, Vegetable existing RL-based approaches rarely focus on scalability or reusability to adapt to the ever-changing markets.These approaches are rigid and unscalable to accommodate the varying

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